They are sixth in the Premier League, but are closer to the relegation zone than to leaders Liverpool, who beat them 3-1 on Sunday.
Their current haul of 26 points from 17 games is their lowest ever at this stage in a Premier League season.
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United have announced that they will appoint a caretaker manager to see the club through to the end of the season before making a permanent appointment in the summer.
Pochettino, meanwhile, is claimed to be keen on replacing Mourinho at United and wants to be considered for the job at the end of the season. The Portuguese manager compiled a record of 84-32-8 and won three trophies in his time with the club: League Cup, Europa League and the Community Shield. "Everyone at the club wishes him all the best in the future".
For the world's biggest club by revenues, it seems it wasn't good enough.
Ex-Liverpool defender Jamie Carragher said on Sky Sports News: "I think you have to go back to the start of the season, and I just thought it was inevitable Jose Mourinho wouldn't be the manager the following season".
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Tottenham, however, are in a strong position as the Argentine signed a five-year contract extension in May which keeps him tied to the club until 2023.
Ironically, Man Utd's next Premier League fixture is a trip to the Cardiff City Stadium on Saturday evening.
United reached the last 16 in the Champions League, where it will play Paris Saint-Germain over two legs in February and March.
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It was a boxing clinic by Alvarez as he would have scored three 10-8 rounds before the finish. Opponent Mauricio Herrera (24-7, 7 KOs), 38, of Riverside, California, was 146 pounds.
Mourinho has had a stellar career - winning titles with Real Madrid and Chelsea.