This picture taken on 28 December 2018 shows a tourist bus which was attacked being towed away from the scene, in Giza province south of the Egyptian capital Cairo. The pyramids are in that region.
A blast hit a bus carrying tourists near the Egyptian pyramids in Giza on Friday, killing at least two and injuring several.
CNN's Hossam Ahmed reported from Cairo and Mohammed Tawfeeq reported and wrote from Atlanta.
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Two people were critically wounded, Prime Minister Mostafa Madbouly said.
Prime Minister Madbouly told reporters that all tourstim trips and their routes are highly secured in a detailed manner by the interior ministry.
No one immediately claimed responsibility.
The injured were taken to the nearby Haram hospital, Reuters news agency reports.
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The white tourist bus could be seen with its windows shattered and surrounded by soot-covered debris, AFP reported. "I don't remember anything after".
Two German tourists were stabbed to death at a hotel in the popular Red Sea resort of Hurghada a year ago.
Egypt has faced a string of bombings in the past few years, with several targeting Egyptian security forces in the country's Sinai peninsula.
Security forces have since February been conducting a major operation focused on the Sinai Peninsula, aimed at wiping out a local IS branch.
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The government says the battle against such groups is a priority as it works to restore stability after the years that followed the 2011 protests.